Numerous studies have examined the pathogenesis of osteoporosis. The causes of osteoporosis include endocrine factors,\nnutritional status, genetic factors, physical factors, and immune factors. Recent osteoimmunology studies demonstrated that the\nimmune system and immune factors play important regulatory roles in the occurrence of osteoporosis, and people should pay\nmore attention to the relationship between immunity and osteoporosis. Immune and bone cells are located in the bone marrow\nand share numerous regulatory molecules, signaling molecules, and transcription factors. Abnormal activation of the immune\nsystem alters the balance between osteoblasts and osteoclasts, which results in an imbalance of bone remodeling and\nosteoporosis. The incidence of osteoporosis is also increasing with the aging of China�s population, and traditional Chinese\nmedicine has played a vital role in the prevention and treatment of osteoporosis for centuries. Chinese medicinal plants possess\nunique advantages in the regulation of the immune system and the relationships between osteoporosis and the immune system.\nIn this review, we provide a general overview of Chinese medicinal plants in the prevention and treatment of osteoporosis,\nfocusing on immunological aspects.
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